Coriandrum sativum and Its Utility in Psychiatric Disorders

The negative impact on worldwide social well-being by the increasing rate of psychiatric diseases has led to a continuous new drug search. Even though current therapeutic options exert their activity multiple neurological targets, these have various adverse effects, causing treatment abandonment. Recent research shown that Coriandrum sativum offers rich source metabolites, mainly terpenes and flavonoids, as useful agents against central nervous system disorders, with remarkable in vitro vivo activities models related pathologies. Furthermore, studies revealed some compounds exhibit chemical interaction γ-aminobutyric acid, 5-hydroxytryptamine, N-methyl-D-aspartate receptors, which are key components pathophysiology associated diseases. clinical evaluations standardized extracts C. scarce; however, one or more its represents an area opportunity test efficacy plant anxiolytic, antidepressant, antiepileptic, sleep enhancer. For this, aim review was based pharmacological offered identified isolated from coriander processes involved achieving effect. In addition, lines technological research, like molecular docking nanoparticles, proposed for future development phytomedicines, bioactive molecules sativum, disorders addressed present study.